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It targets suppressor of cytokine signaling 1 (SOCS1) to alleviate the suppression of JAK/STAT signaling [44], inhibits the transcription factor ETS1 to increase STAT3 activation, strengthens the prodifferentiation effect of cytokines such as IL-23 and IL-6 [45, 46], and suppresses the epigenetic regulator Jarid2 to directly or indirectly relieve the transcriptional repression of Th17-related genes [47]